Recurrent Urinary Tract Infections in dogs: A scoring index for the evaluation of clinical activity and outcome prediction.
The aims of the project are:
1) evaluate the usefulness of potential biomarkers of UTIs;
2) identify risk and predictive factors of the outcome;
3) develop a scoring system that could be predictive of the outcome, of the possibility of obtaining long-term
Microbiological cure or of developing a multidrug resistance infection.
To obtain significative results, data will be collected from dogs affected with recurrent cystitis, evaluated and treated following ISCAID guidelines (2019).
Bacterial urinary tract infections (UTIs) are a common cause of morbidity in dogs. Among them, recurrent bacterial cystitis represents one of the most critical points in clinical practice.
Recurrent bacterial cystitis implies a diagnosis of three or more episodes of clinical bacterial cystitis in the preceding 12 months or two or more episodes in the preceding 6 months. It may result from relapsing, persistent infection, or reinfection.
The lack of identification of an underlying cause, or the impossibility of managing it, can lead to.
Repeated antimicrobial treatments that are unlikely to provide a microbiological cure and could lead to antimicrobial resistance.
Furthermore, the commonly used conventional biomarkers have low sensitivity and specificity for predicting or differentiating UTIs, leading to over or undertreatment.
Field of interest: Veterinary Urology and Nephrology in small animal practice
Collaboration for the provision of medical assistance and support to the management of the 24h Veterinary First Aid / intensive care service in the small animals (dog and cat) unit of the University Veterinary Hospital (OVU).
Master’s Degree in Veterinary Medicine, University of Milan: Title of the experimental thesis: Clinical and analytical validation of a new immunoenzymatic method for the measurement of parathormone in the canine species.
Publications: Orcid ; IRIS-AIR
Supervisor Prof. Paola Scarpa
