Exploring the parasitic extracellular vesicles: advanced diagnostic tools based on miRNAs released in the vertebrate host.
The aim of this project is to investigate the potential use of miRNAs as diagnostic markers for parasitic diseases, including echinococcosis, neosporosis, and tick-borne parasitic infections. miRNAs are small, non-coding RNA molecules that regulate gene expression.
These molecules are carried by extracellular vesicles (EVs), membrane-bound particles released by cells.
Recent studies suggest both miRNAs and EVs play critical roles in parasite-host interactions, making them promising candidates for diagnostic purposes.
By targeting miRNAs within EVs, and deepening their knowledge through molecular techniques, this study could enable the development of highly sensitive diagnostic methods for these parasitic diseases, providing a valuable complementary approach to existing techniques and enhancing early detection and disease management.
MSc in Veterinary Biotechnological Sciences at the University of Milan (UNIMI) – 2024.
BSc in Animal Breeding and Welfare at the University of Milan (UNIMI) – 2022.
Master thesis on the epidemiological analysis of gastrointestinal nematode infections in dairy goats and the evaluation of the frequency of benzimidazole resistance alleles in third-stage larvae.
Deep interest in parasitology and molecular techniques.
Publications: Scopus
Supervisor Prof. Chiara Bazzocchi
Co-supervisor Prof. Maria Teresa Manfredi
